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Do not use estrogen-alone or estrogen with progestins to prevent heart disease, heart attacks, strokes, or dementia decline in brain function. Using estrogen-alone may increase your chances of getting strokes or blood clots, while using estrogens with progestins may increase your chances of getting heart attacks, strokes, breast cancer, or blood clots. Using estrogen-alone or estrogen with progestins may increase your chance of getting dementia, based on a study of women 65 years of age or older.

For more information ask your healthcare provider or pharmacist for advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www. For information call Please see our Privacy Policy for more information. These medicines should be considered for use before estrogen therapy. If you have other medical conditions as well, and are prescribed estrogens for more than one condition, consult your doctor about your treatment plan and its options.

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Use this medication exactly as prescribed. The patch is usually replaced twice a week about every 3 to 4 days , or as directed by your doctor. Follow the dosing schedule carefully. Do not open the sealed pouch container until ready to use. Open the pouch and remove the patch from the protective liner. Apply the patch to a clean, dry, hairless area as directed by your doctor or by the patient information leaflet. This patch should only be applied to certain areas of the body. Different brands of patches are applied to different areas of the body. If you have any questions about where to apply the patch, ask your doctor or pharmacist.

Press the patch firmly against the skin for about 10 seconds to make sure the patch stays on.


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Do not apply to a site that is exposed to sunlight and do not place the patch on the breast. Avoid applying to the waistline since tight clothing may rub the patch off. Do not put the patch on areas where sitting may loosen it.

When it is time to change the patch, remove it and dispose of it properly. Apply a new patch to a different area to prevent skin irritation. It is best to rotate the areas where the patch is applied, allowing at least 1 week in between applications to the same site. If the area around the patch becomes red, itchy, or irritated, try a new site.

If the irritation continues or becomes worse, notify your doctor promptly. If a patch falls off, reapply it or apply a new patch and wear it for the rest of the scheduled period. Read the Patient Information Leaflet available from your pharmacist. Consult your doctor or pharmacist if you have any questions. If any of these effects persist or worsen, notify your doctor promptly.

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An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, severe dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist. This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: undiagnosed abnormal vaginal bleeding, certain cancers e.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: family medical history especially breast lumps and cancer , asthma, diabetes, seizures, migraine headaches, heart disease e. If you will be having surgery or will be confined to a chair or bed for a long period of time e.

Special precautions may need to be taken in these circumstances while you are taking this drug. This drug may make you dizzy; use caution engaging in activities requiring alertness such as driving or using machinery.

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Limit alcoholic beverages. This drug may cause a patchy darkening of the skin on the face melasma. Sunlight may intensify this darkening and you may need to avoid prolonged sun exposure and sunlamps. Consult your doctor regarding use of sunscreens and protective clothing. Cigarette smoking can increase the chance of blood clots while taking this medication especially in women over the age of If this medicine is used in children, their growth pattern should be monitored as this drug might stunt their growth.

This medication must not be used during pregnancy.


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  4. If you become pregnant or think you may be pregnant, inform your doctor immediately. This medication may pass into breast milk and may have undesirable effects on a nursing infant.

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    Therefore, breast-feeding while using this medication is not recommended.

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